Anna Bosch-Vizcaya

Name:
Anna Bosch
Sign: Anna Bosch-Vizcaya
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Predocs

Core binding factor acute myeloid leukemia: the impact of age, leukocyte count, molecular findings, and minimal residual disease.

Core binding factor acute myeloid leukemia: the impact of age, leukocyte count, molecular findings, and minimal residual disease.

PURPOSE: Most patients with acute myeloid leukemia (AML) and genetic rearrangements involving the core binding factor (CBF) have favorable prognosis. In contrast, a minority of them still have a high risk of leukemia recurrence. This study investigated the adverse features of CBF AML that could justify investigational therapeutic approaches. PATIENTS AND METHODS: One hundred and fifty patients (median age 42 yr, range 16-69) with CBF AML (RUNX1-RUNX1T1 n = 74; CBFB-MYH11 n = 76) were prospectively enrolled into two consecutive CETLAM protocols at 19 Spanish institutions.

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Objectius estratègics

- Investigar aspectes biològics, clínics i epidemiològics de les malalties hematològiques

- Desenvolupar projectes de recerca translacional enfocats a trobar factors pronòstics o predictors de resposta a tractament

- Desenvolupar recerca clínica, potenciant la participació a assaigs clínics en malalties hematològiques i participant a grups cooperatius nacionals o internacionals.

 

Principals línies de recerca

Catalan

Red Transfonteriza de immunoterapias personalizadas para Linfomas No Hodgkin

Finançat per: Interreg POCTEFA (EFA281/16/IMLINFO)

Investigador responsable: David Gallardo

Durada: 2018-2020

 

 

Grup de Recerca Reconegut per la Generalitat de Catalunya

Finançat per: Agència de Gestió d’Ajuts Universitaris i de Recerca (AGAUR) (2014 SGR 21)

Durada: des de 2014 fins a 2016

Investigador responsable: David Gallardo

 

Minor Histocompatibility antigens as mediators of immune alloreactivity in human transplantation.

Finançat per: Fundació Marató TV3

Durada: des de 2013 fins a 2015

Investigador responsable: David Gallardo

 

Red de Cáncer. (RD12/0036/0029)

Finançat per: Instituto de Salud Carlos III

Durada: des de 2013 fins a 2015

Investigador responsable: Joan Gil Santano


Papel de los polimorfismos genéticos de CD38 Y CD31 en  la leucemia linfática crónica. 

Finançat per: Fundación Mutua Madrileña

Durada: des de 2011 fins a 2013

Investigador responsable: Josep Mª Roncero

 

Biobanco de aloTPH del GETH. Polimorfismos en antígenos menores de histocompatibilidad y genes moduladores de respuesta inmune como predictores de alorreactividad. (PI11/01690)

Finançat per: Instituto de Salud Carlos III

Durada: des de 2012 fins a 2014

Investigador responsable: David Gallardo

 

 

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Inequalities in mortality in small areas of eleven Spanish cities (the multicenter MEDEA project)

Inequalities in mortality in small areas of eleven Spanish cities (the multicenter MEDEA project)

The objectives of this study are to identify inequalities in mortality among census tracts of 11 Spanish cities in the period 1996-2003 and to analyse the relationship between these geographical inequalities and socioeconomic deprivation. It is a cross-sectional ecological study where the units of analysis are census tracts. We obtained an index of socioeconomic deprivation and estimated SMR by each census tract using hierarchical Bayesian models which take into account the spatial structure.

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